Data collection for Head Position Protocol

The head position protocol requires 14 landmarks placed on medical imaging studies rendered in 3D. During the development of this protocol, the landmarks were acquired using Analyze 12.0. Each landmark should provide (x,y,z) coordinates and the voxel size should be recorded for each imaging study.

The landmarks are used to calculate 17 measurements. These 17 measures are then used in two hybrid GUIDE forest prediction models to classify head position.

Landmarking Protocol

This figure visualizes all landmarks necessary to classify head position.

This figure vizualizes all the landmarks necessary to classify head position. Each landmark should be placed in the anatomical midsagittal point defined for each landmark. These landmarks are used in combination to calculate the measurements described below.

1. Anterior Nasal Spine (ANS)

This figure provides a visual example of the placement of the anterior nasal spine landmark.

The first landmark is placed at the most anterior point of the nasal spine.

2. Posterior Nasal Spine (PNS)

This figure provides a visual example of the placement of the posterior nasal spine landmark.

The second landmark is placed at the most posterior point of the nasal spine.

3. Opisthion (OPI)

This figure provides a visual example of the placement of the opithion landmark.

The third landmark is placed at the most anterior-inferior point on the posterior margin of the foramen magnum.

4. Spinous Process of C7 (SpPro7)

This figure provides a visual example of the placement of the spinour process of C7 landmark.

The fourth landmark is placed at the most posterior point on the spinous process of C7. In the case of bifid spinous processes, the landmark should be placed on the midpoint of where the two sides deviate, instead of the exact most posterior aspect.

5. Posterior Superior corner of the apex of the axis, C2 (PSA)

This figure provides a visual example of the placement of the posterior superior apex of the axis (C2) landmark.

The fifth landmark is placed at the most posterior and superior conrner of the apex of the odontoid at the anatomical midline. This landmark should be placed at the superior corner of the posterior border of C2.

6. Anterior Tubercle of Atlas, C1 (AT1)

This figure provides visual example of the placement of the anterior tubercle of the atlas (C1).

The sixth landmark is placed at the most medio-anterior point of C1 denoting the anterior tubercle of the atlas, C1.

7-11. Posterior Inferior Margin of vertebral body

For C2 and C4 to C7, place the landmarks on each vertebrae at the most posterior and inferior point of the vertebral body.

C2

This figure provides visual example of the placement of the C2pi landmarks.

The seventh landmark is placed at the most posterior and inferior point of the C2 vertebral body in the anatomical midsagittal plane.

C4

This figure provides visual example of the placement of the C4pi landmark.

The eight landmark is placed at the most posterior and inferior point of the C4 vertebral body in the anatomical midsagittal plane.

C5

This figure provides visual example of the placement of the C5pi landmark.

The ninth landmark is placed at the most posterior and inferior point of the C5 vertebral body in the anatomical midsagittal plane.

C6

This figure provides visual example of the placement of the C6pi landmark.

The tenth landmark is placed at the most posterior and inferior point of the C6 vertebral body in the anatomical midsagittal plane.

C7

This figure provides visual example of the placement of the C7pi landmark.

The eleventh landmark is placed at the most posterior and inferior point of the C7 vertebral body in the anatomical midsagittal plane.

12. Posterior Superior Margin of C7 vertebral body

This figure provides a visual example of the placement of the C7ps landmark.

The twelfth landmark is placed at the most posterior and superior point of the C7 vertebral body in the anatomical midsagittal plane.

13-14. Anterior Inferior Margin of C2 and C7 vertebral bodies

For C2 and C7, place the landmarks on each vertebrae at the most anterior and inferior point of the vertebral body.

C2

This figure provides visual example of the placement of the C2ai landmark.

The thirteenth landmark is placed at the most anterior and inferior point of the C2 vertebral body in the anatomical midsagittal plane.

C7

This figure provides visual example of the placement of the C7ai landmark.

The fourteenth landmark is placed at the most anterior and inferior point of the C7 vertebral body in the anatomical midsagittal plane.

Measurements

This protocol utilizes 17 measurements to quantify head position. These measures assess both the face plane and the neck position.

Head Measures or Face Plane Measures

V1. ANS-PNS Plane

This figure provides visual example of the ANS-PNS plane angle.

The angle of the nasal spine plane defined by the anterior nasal spine (ANS, 1) and the posterior nasal spine (PNS,2) landmarks subtended with the horizontal plane of the imaging study.

V2. Maxillo-Pharyngeal (MP) Angle

This figure provides visual example of the MP angle.

The angle of intersection between the PNS (2) - anterior tubercle of C1 (AT1, 6) line and the AT1 (6) - anterior inferior point of C2 (C2ai, 13) line.

V5. Modified Bhalala head tilt angle

This figure provides visual example of the modified Bhalala angle.

The angle of intersection between the PNS (2) - opisthion (OPI, 3) line and the OPI (3) - C7 spinous process (4) line.

V7. C2 Angle

This figure provides visual example of the C2 angle.

The angle of intersection between the posterior border of C2 (7, 5) line and the ANS (1) - PNS (2) plane.

Neck Measures

Antero-Posterior Measures

The anterior and posterior distances are calculated between the inferior landmarks of C2 to C7 and used for two of the head position measures. To ensure the distance measurements are calculated in millimeters (mm), the coordinates should be multiplied by the voxel size of each imaging study.

This figure provides visual example of the Anterior and Posterior distances.
V3. Antero-Posterior Distance Ratio

The ratio of the anterior to the posterior distances from the inferior borders of C2 to C7.

V4. Antero-Porsterio Distance Difference

The difference between the anterior and posterior distances from the inferior borders of C2 to C7.

Various Lower Cervical Spine Angle

The lower cervical spine has been measured using various combinations of landmarks. This protocol includes five variations allowing the complexity of neck mobility to be assessed. Each variation is calculated at the angle of intersection between the ANS (1) - PNS (2) plane with the posterior boarder of the cervical vertebrae defined as follows:

V8. C6-C4 angle
This figure provides visual example of the C7pi to C6pi angle.

This variation of the lower cervical spine angle defines the posterior border by the posterior inferior of C6 (10) to the posterior inferior of C4 (8).

V9. C7 angle
This figure provides visual example of the C7 PI-PS angle.

This variation of the lower cervical spine angle defines the posterior border by the posterior inferior of C7 (11) to the posterior superior of C7 (12).

V10. C7-C6 angle
This figure provides visual example of the C7pi to C6pi angle.

This variation of the lower cervical spine angle defines the posterior border by the posterior inferior of C7 (11) to the posterior inferior of C6 (10).

V11. C7-C5 angle
This figure provides visual example of the C7pi to C5pi angle.

This variation of the lower cervical spine angle defines the posterior border by the posterior inferior of C7 (11) to the posterior inferior of C5 (9).

V12. C7-C4 angle
This figure provides visual example of the C7pi to C6pi angle.

This variation of the lower cervical spine angle defines the posterior border by the posterior inferior of C7 (11) to the posterior inferior of C4 (8).

Upper and lower cervical spine difference

The change in angles along the cervical spine assist with determining the neck position. Following are multiple angle difference measures.

V13. C2 v C6-C4 difference

This measure calculates the difference between the C2 angle (V7) and the C6-C4 angle (V8).

V14. C2vC7 difference

This measure calculates the difference between the C2 angle (V7) and C7 angle (V9).

V15. C2vC7-C6 difference

This measure calculates the difference between the C2 angle (V7) and C7-C6 angle (V10).

V16. C2vC7-C5 difference

This measure calculates the difference between the C2 angle (V7) and C7-C5 angle (V11).

V17. C2vC7-C4 difference

This measure calculates the difference between the C2 angle (V7) and C7-C4 angle (V12).